ACTH-Dependent Cushing's Syndrome - Endocrine Biochemical Tests (Differential Diagnosis)

Biochemical (Endocrine) Tests for ACTH-Dependent Cushing's Syndrome:

• High dose 2 day dexamethasone suppression test
• 8mg overnight dexamethasone suppression test
• Metyrapone stimulation test
• Peripheral CRH stimulation test
• Desmopressin stimulation test
• Bilateral inferior petrosal sinus sampling with CRH stimulation test

Glossary:
CRH = Corticotropin releasing hormone
Desmopressin = Modified form of the normal human hormone arginine vasopressin.
Dexamethasone = Potent synthetic glucocorticoid steroid drug.
Metyrapone = Inhibits steroid 11β-hydroxylase blocking cortisol synthesis.

Tags: ACTH - Cortisol - CRH - Cushing's Syndrome - Desmopressin - Dexamethasone - Inferior Petrosal Sinus - Metyrapone - Test
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